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Filler Dissolving Treatment

Hyalase filler dissolving by GMC Specialist Register plastic surgeons. Reverse unwanted, migrated, or problematic HA filler. Emergency vascular rescue available. From £395 small areas, £695–£995 full face. CQC-regulated Baker Street clinic.

Hyalase Filler Dissolving at Centre for Surgery, London

Hyalase filler dissolving in summary: Hyalase (hyaluronidase) is the enzyme used to dissolve hyaluronic acid (HA) — the only effective reversal option for HA-based filler. At Centre for Surgery, all Hyalase treatments are performed by GMC Specialist Register plastic surgeons — including for emergency vascular complications where rapid hyaluronidase administration is the standard rescue protocol. Treatment takes 15–30 minutes; results visible within hours, settling fully over 1–2 weeks. From £395 small areas, £695 moderate, £995 comprehensive. Emergency same-day appointments available for vascular complications. CQC-regulated Baker Street clinic.

Hyalase is sometimes treated as a casual aesthetic procedure — but the clinical decisions around dosing, dissolution strategy, and emergency response require surgical-level judgment. Common scenarios where the surgeon credential matters: managing migrated lip filler that has spread above the natural lip border (anatomical knowledge of perioral musculature); deciding between conservative dissolution and aggressive dissolution; pre-surgical dissolution where the goal is removing existing filler before or ; revision cases (dissolving filler from elsewhere where the original product and placement aren’t fully known); and emergency vascular rescue where dosing decisions affect outcomes substantially.

If you’ve had filler from any clinic and develop any of the following, contact us immediately on : skin pallor, blanching, or mottling on or near the filler area; severe pain disproportionate to the procedure; vision changes (blurring, dark spots, vision loss in one or both eyes); severe headache or neurological symptoms; or rapidly evolving skin discolouration.

The window for hyaluronidase rescue is hours, not days — earlier action substantially improves outcomes. We hold Hyalase on site for emergency administration. We accept emergency same-day vascular cases regardless of where the original filler was administered. If unable to reach us, attend an emergency department immediately. Time matters more than the choice of clinic.

What Is Hyalase (Hyaluronidase)?

Hyalase is the trade name for hyaluronidase — an enzyme that breaks down hyaluronic acid (HA). Understanding what Hyalase is, how it works, and what it can and cannot do is the foundation of safe filler dissolution.

Hyaluronic acid is a sugar molecule found naturally throughout the body — in skin, joints, eyes, and connective tissue. Most modern dermal fillers are made of cross-linked HA — a gel form that holds its shape against tissue pressure to add volume.

Hyaluronidase is an enzyme that cleaves HA molecules into smaller fragments. Hyalase is a sterile, pharmaceutical-grade preparation of hyaluronidase formulated for injection. When Hyalase is injected into an area where HA filler has been placed, it breaks down the HA molecules — both the cross-linked filler and (at higher doses) the body’s natural HA in the surrounding tissue. The fragments are then absorbed and excreted naturally.

Hyalase begins working within minutes of injection. Visible reduction in filler volume usually appears within hours. The full dissolution process typically completes over 24–72 hours. The Hyalase enzyme itself is broken down by the body within approximately 24–48 hours after injection — meaning new HA filler placed after this period (we recommend 2 weeks for full clearance and tissue settling) is unaffected.

Hyalase dissolves HA-based filler products. This includes most modern dermal fillers used at our clinic and most clinics. The dissolution effect is independent of brand — Hyalase works on cross-linked HA regardless of which manufacturer’s product was used.

Hyalase has no effect on:

For non-HA fillers, no equivalent enzymatic reversal exists. This is one of the most important reasons we use HA-only fillers for facial cosmetic work — reversibility is a critical safety property, particularly for high-risk areas.

Hyalase comes as a sterile lyophilised (freeze-dried) powder in single-use vials. Before injection, the surgeon reconstitutes it with sterile saline at the appropriate concentration for the dose required. Concentration and dosing are determined by the area being treated and the clinical goal — conservative dissolution for cosmetic refinement; higher concentration for emergency vascular rescue.

In the UK, hyaluronidase is a prescription-only medicine. It can only legally be administered by a doctor, dentist, nurse prescriber, or other appropriate prescriber, OR under a prescriber’s direction. Despite the legal framework, the injectables market has wide variation in who actually prescribes and administers — patients should verify the credentials of whoever delivers their treatment. At Centre for Surgery, all Hyalase is administered by GMC Specialist Register plastic surgeons.

When You Need Filler Dissolving

Patients consult for Hyalase for many reasons — cosmetic, complication-related, and emergency. Below are the most common scenarios, with notes on what dissolution can and can’t achieve in each case.

The most common modern indication. Lip filler (particularly when over-injected or placed superficially) can spread beyond the lip border into the surrounding tissue — producing an upper “moustache” of HA, a “shelf” appearance above the lip, or filling of the philtrum. This is one of the most common reasons patients seek dissolution. Hyalase reliably reverses migration, returning the lip border to its natural position. After dissolution, patients can choose to remain natural or have fresh, more conservative placement at our clinic.

“Duck lip” appearance, excessive volume, distorted shape — these are reversible with Hyalase. Many patients seek dissolution after years of cumulative lip filler that has gradually become more pronounced than they intended.

“Pillow face” appearance, exaggerated cheekbone projection, or filler that has descended creating jowl-like lower-face fullness. Cheek filler dissolution requires careful dosing — too much Hyalase can dissolve native HA producing temporary mid-face hollowing.

The under-eye region is one of the most common areas for filler dissatisfaction: Tyndall effect (bluish tinge from superficial HA placement), puffiness, persistent swelling, lumpiness, or simply unsatisfactory aesthetic outcome. See our page for detailed clinical context. Tear trough filler dissolution requires particularly careful technique because the area is anatomically delicate.

The nose is the highest-risk facial filler area, and unsatisfactory non-surgical rhinoplasty outcomes are a common reason for revision. Hyalase reliably dissolves HA filler from the nose. See our page for the clinical context.

Modern jawline and chin filler trends have produced some patients with unnaturally heavy lower faces. Hyalase reliably dissolves HA filler in these areas. See and .

Filler that hasn’t smoothed evenly can produce visible or palpable lumps. Initial management is typically gentle massage; if this doesn’t resolve the lump, Hyalase dissolution of the affected area is appropriate.

A bluish tinge under the skin caused by HA filler placed too superficially — most commonly in the tear trough but possible anywhere. Hyalase reliably reverses this.

Some patients have had filler treatments every 6–12 months for many years, with cumulative volume that has subtly distorted facial proportions. Hyalase dissolution can reset the face to native anatomy, allowing either a natural look or fresh, more thoughtful filler planning.

For patients planning , , , or other facial surgery, dissolving existing filler before surgery allows the surgeon to assess your native anatomy accurately. This produces better surgical results.

We see significant numbers of revision patients — those who’ve had filler elsewhere and now want it reversed. We dissolve filler from elsewhere as readily as our own. The revision consultation includes assessment of what was injected (where you remember and where it’s now visible), where dissolution is needed, and whether complete or partial dissolution is appropriate.

This is the most clinically critical Hyalase indication. Vascular events from HA filler require immediate hyaluronidase administration — the window is hours, not days. Symptoms requiring immediate emergency contact are detailed in Block 0 above and the dedicated emergency section below. Same-day appointments available.

For elective dissolution of new filler, we recommend waiting at least 2–3 weeks after the original injection before considering Hyalase — this allows initial swelling and product migration to settle, so the assessment is of the actual filler placement rather than transient effects. The exception is emergency complications or significant problems requiring urgent reversal — in these cases, Hyalase is administered immediately regardless of how recent the original injection was.

Who Is Suitable for Hyalase Treatment?

Adults aged 18+ who have had HA-based dermal filler and are seeking reversal are typically suitable. Suitability is confirmed at face-to-face consultation with the plastic surgeon, with particular attention to allergy history.

This is the most important screening point for Hyalase treatment. Hyaluronidase is structurally similar to enzymes found in bee and wasp venom. Patients with a history of severe allergic reaction (anaphylaxis) to bee or wasp stings have a higher risk of allergic reaction to Hyalase.

For elective Hyalase treatment in patients with a relevant allergy history, we typically:

For emergency vascular complications in patients with bee/wasp allergy, the calculation changes — Hyalase is still typically administered because the alternative (untreated vascular event with potential blindness or skin necrosis) is far more serious.

We’re honest with patients about what dissolution will and won’t achieve:

The mandatory two-week cooling-off period applies for elective dissolution. For emergency vascular complications, this is bypassed and treatment proceeds immediately.

Common areas for treatment with Hyalase

Hyalase can dissolve HA filler in any anatomical area where filler has been placed. Below are the most common indications, with notes on what’s specific to each area.

Most common Hyalase indication. See .

Common scenarios for lip dissolution:

Dosing approach: typically conservative at first session because over-dissolution of native lip HA produces temporary thinning. Patients with significant migration may need more aggressive dosing in the migrated area while preserving lip body filler if appropriate.

See and .

Common scenarios for cheek dissolution:

Dosing approach: targeted dissolution of the affected area; care to avoid over-dissolution producing temporary mid-face hollowing.

See .

Common scenarios for under-eye dissolution:

Particular technical care: the under-eye region has delicate anatomy and surgeon-led dosing is particularly important. Some under-eye filler problems are best addressed by dissolution rather than additional filler attempts.

See .

The nose is the highest-risk facial filler area, and reversal is one reason we use HA-only filler for nasal work. Common scenarios for nasal dissolution:

See and .

Common scenarios:

See . Less commonly dissolved because temple filler placement is typically deep and well-contained, but Hyalase is appropriate for over-injection or asymmetry.

Less commonly dissolved as standalone areas, but addressed when combined with other facial areas in comprehensive dissolution.

HA filler used in the hand dorsum for vein camouflage and skin quality can be dissolved if needed. Less common indication.

Some patients have HA filler in non-facial areas. Hyalase works equally well — though the dosing and technique are tailored to the area.

Pre-Treatment Precautions Before Hyalase

Pre-treatment preparation matters for both safety and outcomes. The instructions below apply to elective dissolution; for emergency vascular cases, treatment proceeds immediately without these preparatory steps.

At consultation, please disclose:

This is the single most important pre-treatment screening point for Hyalase.

Avoid scheduling vaccines for 3 weeks before and 3 weeks after Hyalase treatment. Vaccines and Hyalase can interact in ways that affect both the treatment outcome and the immune response.

If you have a history of cold sores around or within the treatment area (particularly around the lips), inform us at consultation. Antiviral medication (typically aciclovir) is prescribed prophylactically for 3 days before and 5 days after treatment to prevent a flare-up. The trauma of injection can trigger cold sore reactivation.

For 3–5 days before treatment:

If you have an active skin infection, inflammation, cold sore, or significant breakout in the treatment area, treatment should be postponed until resolved. This is to minimise infection risk.

Disclose all current medications and supplements at consultation. Specific concerns:

Smoking impairs healing and is best minimised. Alcohol increases bruising — avoid for 24 hours minimum before treatment.

Stay well-hydrated in the days before treatment. Good hydration supports tissue healing and recovery.

Many patients find filler dissolution emotionally significant. The 2-week settling period after dissolution can be psychologically difficult — appearance changes gradually and feelings about the new look may shift. We support patients through this. Some patients prefer to have someone with them at the appointment and during the first few days afterwards.

The Hyalase Filler Dissolving Procedure

The Hyalase injection itself takes 15–30 minutes depending on the number of areas being treated. Allow 45 minutes total for the appointment including consultation review, photographs, numbing cream application, and aftercare advice.

The surgeon reconstitutes the Hyalase product immediately before treatment using sterile saline. The concentration is determined by the area being treated and the clinical goal:

The protocol differs significantly:

Discomfort is mild with numbing cream — most patients describe it as 2–3 out of 10. Some patients describe a sensation of warmth or “fizzing” in the treated area as dissolution begins. There may be brief sharp sensations as the needle enters; these resolve quickly. Mild pressure as the Hyalase is injected.

You’ll be observed for 15 minutes after treatment to monitor for any allergic reaction. While Hyalase reactions are rare, they can occur — and the post-treatment observation period allows immediate response if needed. For emergency vascular cases, observation is significantly longer.

A follow-up review at 2 weeks is included in the treatment cost. At this review:

Some patients need more than one session for complete dissolution. Reasons:

When a second session is needed, the surgeon discusses this at the 2-week review and the appointment is scheduled at the patient’s convenience. The 50% second-session price applies.

Hyalase Aftercare and Recovery

Recovery in summary: Mild downtime. Resume work and most normal activities the same or next day. The dissolution process produces local swelling that’s typically more pronounced than after a typical filler injection — settles within 24–72 hours. Bruising at injection points may take 5–7 days to resolve. Final settled appearance at 1–2 weeks.

Wait at least 2 weeks from Hyalase treatment before any new HA filler. The waiting period allows:

New filler placed too soon will be partially dissolved by residual enzyme — wasted product and treatment failure.

Normal: mild swelling for 24–72 hours, mild bruising for 5–7 days, mild tenderness, gradual reduction in filler volume, occasional mild itching at injection points.

Contact us immediately on if you experience:

For symptoms suggesting anaphylaxis (difficulty breathing, throat tightness, severe widespread swelling), call 999 immediately and use any available adrenaline auto-injector if you have been prescribed one. Do not wait to contact us first if there’s any concern about airway or breathing.

After dissolution, your skin returns to its native baseline over 1–2 weeks. Some patients notice their lips or other treated areas feel slightly “different” in the early days — this is normal and resolves as tissue settles. The treated tissue has the same response to future filler as it did before — Hyalase doesn’t damage the tissue’s ability to receive filler in the future.

What to Expect — Hyalase Results and Timeline

Hyalase produces visible results faster than most aesthetic injectables — but the full settled appearance takes 1–2 weeks. Below is what to expect at each stage.

Day 0: lips look slightly smaller and possibly slightly swollen at injection points. Day 3: clear reduction in volume; some swelling. Day 7: substantial settling; lip border re-emerging if migration was the issue. Day 14: final settled appearance — typically natural lip shape and proportion.

Day 0: slight reduction in cheek projection; minor swelling. Day 3: clearer reduction visible. Day 7: significant settling. Day 14: final settled mid-face contour.

Day 0: variable — sometimes immediate visible change, sometimes initial swelling masks the result. Day 3: under-eye swelling typically present. Day 7: substantial settling. Day 14: final result — typically resolution of Tyndall effect and excess volume.

Day 0: mild swelling may temporarily mask the result. Day 3: clear reduction visible. Day 7: substantial settling. Day 14: final settled nasal shape — typically return to pre-filler shape.

In most cases, a single Hyalase session produces complete dissolution of recent HA filler. Some scenarios where a second session is appropriate:

The 2-week review identifies whether a second session is appropriate; if so, it’s provided at 50% of the original session cost.

In most cases, yes — your appearance returns to your pre-filler baseline within 2 weeks of complete dissolution. Some honest caveats:

If after 2 weeks you’re unhappy with the dissolved appearance, options include:

We discuss all options honestly at the 2-week review, with recommendation based on what will deliver what you’re looking for.

Risks and Potential Complications of Hyalase Treatment

Hyalase is generally well-tolerated when administered correctly. The complication profile is well-documented and most issues are mild and transient. Below is the honest picture, with notes on how risk is mitigated through surgeon-led delivery.

The complication risk is significantly reduced by:

While anaphylaxis from Hyalase is rare, our clinic is fully equipped for emergency response — including adrenaline auto-injector availability, oxygen, and full resuscitation capability. The 15-minute post-treatment observation period is specifically designed to allow recognition and immediate response if a reaction begins.

For mild localised reaction (redness, itching at injection points beyond expected): contact the clinic on ; antihistamines may be recommended.

For widespread reaction (hives across body, breathing difficulty, throat tightness, dizziness): this is anaphylaxis. Call 999 immediately. Use any prescribed adrenaline auto-injector if you have one. Get to an emergency department.

For vascular signs (skin pallor, blanching, mottling, vision changes): contact the clinic immediately and seek emergency care if not reachable.

Hyalase is fully metabolised within 24–48 hours of injection. There is no long-term residual product. The treated tissue’s ability to receive future filler is preserved — Hyalase doesn’t damage the tissue or affect future filler placement.

Hyalase Filler Dissolving Cost in London — Plastic Surgeon-Led Pricing

Hyalase pricing at Centre for Surgery is tiered by area and complexity. Pricing reflects the GMC Specialist Register plastic surgeon credential, CQC-regulated clinic standards, emergency response capability, and the included 2-week review with second session at 50% if needed.

The surgeon confirms the appropriate tier at consultation based on the assessment.

If a second session is needed (some patients with very firm or older filler, or those needing complete dissolution of large volumes), the second session is provided at 50% of the original session cost. The 2-week review identifies whether a second session is appropriate.

For emergency vascular events (skin pallor, severe pain, vision changes), same-day appointments are available. Cost is not a barrier to emergency care. Pricing is discussed at the time depending on the situation, but treatment is administered first when clinically urgent. We accept emergency cases regardless of where the original filler was administered.

Every quote at Centre for Surgery includes:

There are no hidden charges. The price quoted at consultation is the price you pay.

Standard nurse-injector Hyalase pricing in London ranges £150–£300 per session. Our pricing reflects:

For routine cosmetic dissolution, nurse-injector pricing may be adequate; for complex revision, post-elsewhere problems, vascular emergencies, or pre-surgical dissolution, surgeon-led delivery delivers fundamentally different clinical capability.

For patients combining Hyalase with new filler placement (typically 2 weeks later):

For elective dissolution and combination treatments, Chrysalis Finance offers payment plans. 0% APR options are available subject to status, with longer terms at variable rates.

Indicative monthly costs at 0% APR over 12 months:

Note: emergency dissolution for vascular complications is not typically financed because it’s urgent — treatment proceeds and payment is arranged afterwards.

Full finance details are on our , or speak to a patient coordinator on .

Why Choose Centre for Surgery for Hyalase Filler Dissolving

Hyalase is sometimes treated as a casual aesthetic procedure — but the clinical decisions around dosing, dissolution strategy, allergy screening, and emergency response require surgical-level judgment. The reason to choose plastic-surgeon-led Hyalase at Centre for Surgery is the combination of safety capability, clinical judgment, and integration with the wider treatment pathway.

Every Hyalase treatment at Centre for Surgery is performed by a plastic surgeon on the GMC Specialist Register — the same surgeon who would perform your , , , or other facial surgery. Surgeon-level decision-making matters for filler dissolving — for dosing judgment, anatomical knowledge, complex revision cases, and emergency response.

This is one of the most clinically important aspects of our Hyalase service. Vascular events from HA filler require immediate hyaluronidase administration — the window is hours, not days. We hold hyaluronidase on site at our Baker Street clinic for emergency administration. We accept emergency same-day vascular cases regardless of where the original filler was administered. Full emergency response capability — adrenaline, oxygen, resuscitation equipment — is available. This level of emergency preparedness is uncommon outside hospital settings, and is the central reason for surgeon-led delivery in our model.

The bee/wasp venom allergy contraindication is the single most important screening point for Hyalase treatment. We screen for this carefully at consultation and conduct skin patch testing where relevant. Our cautious clinical position: in patients with significant bee/wasp allergy history seeking elective dissolution, we discuss alternative options including waiting for natural filler degradation. This screening is sometimes neglected in less rigorous settings and can have serious consequences.

We tell patients honestly when dissolution isn’t the right approach, when expectations need adjusting, or when natural lip/face anatomy means dissolution will produce less volume than they remember pre-filler. We don’t push patients toward fresh filler placement after dissolution — many leave happier filler-free, and we support that decision.

We offer the complete range — , , , , , , , , , , and — alongside surgical rejuvenation. The dissolution consultation can address fresh filler planning if wanted, with consistent surgical care across the entire pathway.

We use HA-only fillers for facial cosmetic work — never Radiesse, Sculptra, PMMA, or silicone. This means everything we place can be reversed with Hyalase if needed. The reversibility is a critical safety property, particularly for high-risk areas like the nose and tear trough.

We see significant numbers of revision patients — those who’ve had filler from elsewhere with unsatisfactory or problematic results. We dissolve filler from elsewhere as readily as our own. The revision consultation includes thorough assessment of what’s been injected and what dissolution strategy is appropriate.

Centre for Surgery is a private clinic on Baker Street, London. The same clinical governance standards required of any private hospital apply at our clinic — particularly important for emergency vascular case management.

Our default approach is conservative initial dosing with the option of a second session if needed (at 50% of the original session cost). This is preferable to aggressive single-session dosing because over-dissolution producing native HA loss is harder to manage than under-dissolution.

The clinic is at 95–97 Baker Street, Marylebone, London W1U 6RN, a short walk from Baker Street tube station (Jubilee, Metropolitan, Circle, Hammersmith & City, and Bakerloo lines).

A face-to-face consultation with the plastic surgeon is required before elective dissolution. Emergency vascular complication appointments are accepted same-day without consultation — call us immediately if you have any signs of a vascular event from filler.

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Email:
Address: 95–97 Baker Street, Marylebone, London W1U 6RN
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Finance options are available from , including 0% APR, subject to status.

FAQs

What To Expect

Initial Consultation with the Plastic Surgeon Your consultation at Centre for Surgery for filler dissolving is conducted by a GMC Specialist Register plastic surgeon — not a nurse, dentist, or non-specialist doctor. The consultation is the most important step in ensuring safe, appropriate dissolution. Thorough Assessment of the Filler in Place The surgeon examines the areas where filler has been injected, identifying both the obvious filler deposits and any signs of migration, asymmetry, lumpiness, Tyndall effect, or vascular compromise. For revision cases (filler from elsewhere), this assessment is particularly important — what was injected, when, and where may not match what’s visible now. Discussion of Your Concerns and Goals You explain why you’re seeking dissolution — whether it’s dissatisfaction with results, migration, lumps, planned re-treatment, or something else. The surgeon clarifies what’s possible: complete dissolution to baseline, partial dissolution to address specific concerns, or full reset before fresh placement. Allergy and Medical History Screening Critical screening for: bee or wasp sting allergy (relative contraindication for Hyalase due to molecular similarity); previous Hyalase reactions; pregnancy or breastfeeding (contraindication); bleeding disorders; medications including blood thinners; autoimmune conditions; and any other relevant medical history. A skin patch test may be appropriate in patients with relevant allergy history. Determining the Treatment Plan Based on assessment, the surgeon designs the dissolution plan: which areas to treat, how much Hyalase to use, whether to dose conservatively (recommended at first session) or more aggressively, and whether one session or two will be needed. For revision cases, the plan also considers whether new filler placement is wanted afterwards (typically waited 2 weeks). Transparent Cost Breakdown The cost is confirmed at consultation — £395 small area, £695 moderate, £995 comprehensive — with the 50% second-session price clearly stated. There are no hidden charges. The 2-week review is included. Cooling-Off Period For elective dissolution, a 14-day cooling-off period applies between consultation and treatment. For emergency vascular complications, this is bypassed — treatment is administered immediately.

How To Prepare for Hyalase Treatment Following these guidelines minimises bruising, swelling, and complication risk. They apply to elective dissolution — for emergency vascular cases, treatment proceeds immediately without these preparatory steps. 48 Hours Before Treatment Avoid alcohol — increases bruising and swelling. Stop NSAIDs (ibuprofen, aspirin) — these are blood thinners and increase bruising. Paracetamol is fine if you need pain relief during this period. Avoid intensive facial treatments (peels, microneedling, laser) on the treatment area. Vaccine Schedule Avoid scheduling vaccines for 3 weeks before and 3 weeks after Hyalase treatment. Vaccines and Hyalase can interact in ways that affect both the treatment outcome and the immune response. Cold Sore History If you have a history of cold sores around or within the treatment area (particularly around the lips), inform us at consultation. Antiviral medication (typically aciclovir) is prescribed prophylactically for 3 days before and 5 days after treatment to prevent a flare-up. The trauma of injection can trigger cold sore reactivation. The Day of Treatment Eat a normal meal beforehand — fasting can increase the risk of feeling faint during treatment. Avoid alcohol on the day. Bring a list of any current medications and supplements. Wear comfortable clothing. Bring photographs of yourself before any of the filler in place was injected, if you have them — these help the surgeon understand your baseline anatomy. Allergy Disclosure At final consent before treatment, the surgeon will reconfirm the screening for bee/wasp allergy and Hyalase contraindications. If anything relevant has changed since consultation, disclose it. Emotional Preparation Many patients find filler dissolving emotionally significant — particularly if they’re reversing significant change or dealing with a treatment outcome that’s caused distress. The clinical team understands this. The 2-week settling period after dissolution can also be psychologically difficult — the appearance changes gradually and you may have lots of feelings about the new look. We support you through this.

The Hyalase Treatment Procedure The injection itself takes 15–30 minutes depending on the number of areas being treated. Allow 45 minutes total for the appointment including consultation review, photographs, numbing cream application, and aftercare advice. Before Treatment Begins Photographs of the treatment area for record and 2-week review comparison. The plastic surgeon reviews the agreed treatment plan and confirms the areas to treat. Topical numbing cream is applied for 30 minutes. Skin is cleansed with antiseptic at injection points. The Hyalase Injection The Hyalase product is reconstituted with sterile saline at the appropriate concentration for the dose required. The surgeon injects directly into the areas where HA filler is to be dissolved. Small volumes are deposited at multiple points across the target area to ensure even distribution. The needle used is fine (typically 30G), causing minimal discomfort once numbing has taken effect. For Vascular Emergency Cases The protocol differs significantly for emergency vascular events. Higher concentrations and larger volumes of Hyalase are used. The treatment area extends beyond the immediate site of filler placement to address the vascular territory. Repeat dosing may be needed at intervals over hours. Emergency cases bypass the standard cooling-off period and consent is taken in the moment. Light Massage After Injection For elective dissolution, the surgeon gently massages the treated area to help distribute the Hyalase and accelerate dissolution. What You’ll Feel Discomfort is mild with numbing cream — most patients describe it as 2–3 out of 10. Some patients describe a sensation of warmth or “fizzing” in the treated area as dissolution begins. Post-Injection Observation You’ll be observed for 15 minutes after treatment to monitor for any allergic reaction (rare but possible). For emergency cases, observation is longer. Immediate Visible Effects Reduction in filler volume may be visible within hours. Final settled result at 1–2 weeks once swelling has resolved. The 2-Week Review A follow-up review at 2 weeks is included in the treatment cost. The surgeon assesses dissolution completeness, discusses any concerns, and confirms whether a second session is needed (offered at 50% of original session cost) or whether new filler placement is wanted (waited at least 2 weeks total from dissolution).

Aftercare and Recovery Recovery from Hyalase treatment is straightforward but not zero — the dissolution process produces local swelling that’s typically more pronounced than the original filler injection. The instructions below ensure optimal outcomes. The First 12 Hours Avoid touching, rubbing, or applying pressure to the treated area. Don’t apply makeup. The Hyalase needs to remain in place to work effectively — disturbing the area can cause migration of the enzyme to unintended areas. The First 24 Hours Avoid vigorous exercise — increases blood flow and swelling. Avoid alcohol — increases bruising. Stay upright; don’t lie flat. Sleep with your head slightly elevated (especially for under-eye and tear trough dissolution). Take paracetamol for any mild discomfort. Avoid ibuprofen and aspirin for 48 hours. Days 2–7 Resume normal activities including light exercise. Continue avoiding intensive facial treatments. Bruising and swelling should settle progressively. Light makeup is fine to camouflage if needed. Avoid extreme heat — saunas, hot tubs, hot yoga, prolonged direct sun exposure for 2 weeks. Days 7–14 The final settled appearance becomes apparent. Don’t judge the final result before 2 weeks — early appearance is affected by swelling and partial dissolution. Attend the 2-week review appointment. Skincare Resume normal skincare routine the day after treatment. Avoid retinol, glycolic acid, or other strong actives on the treated area for 1 week. Use SPF on the treated area when outdoors. Smoking and Alcohol Smoking impairs healing and is best avoided during recovery. Alcohol increases swelling and bruising — avoid for 24 hours minimum. What’s Normal vs What Needs Attention Normal: mild swelling for 24–72 hours, mild bruising for 5–7 days, mild tenderness, the gradual reduction in filler volume. Contact us immediately on if you experience: severe pain disproportionate to the procedure; rapidly evolving severe swelling beyond what’s expected; signs of allergic reaction (widespread itching, rash, difficulty breathing, throat tightness — rare but important to recognise); skin pallor, blanching, or mottling in or beyond the treatment area; signs of infection (increasing redness, warmth, pus, fever beyond 24 hours); or any other concerning symptoms. If a New Filler Placement Is Planned Wait at least 2 weeks from Hyalase treatment before any new HA filler. The waiting period allows residual hyaluronidase to clear, swelling to settle, and the surgeon to accurately plan new placement. New filler placed too soon will be partially dissolved by residual enzyme — wasted product and treatment failure.

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